Mysoline is the brand name for the barbiturate primidone, an incredibly potent sedative that was originally used to treat epilepsy, anxiety, insomnia, and other sleep disorders. Like other barbiturates, Mysoline is rarely prescribed today, due to the many harmful side effects associated with its use and its very high potential for abuse, addiction, and overdose.
Currently, Mysoline is one of a handful of barbiturates still in use, and it’s only utilized by doctors for patients who have previously been resistant to safer medications. Nonetheless, Mysoline is still legally available, and it’s also illicitly sold online. Therefore, it’s still a very real danger.
As a barbiturate and central nervous system (CNS) depressant, Mysoline works by creating powerful feelings of relaxation, sedation, and intoxication by slowing down activity within the nervous system.
By increasing the levels of a neurotransmitter called gamma-aminobutyric acid (GABA), your brain can regulate feelings of anxiety, stress, and fear by inhibiting the nerve impulses that carry these feelings to the brain. Mysoline mimics this natural GABA flow, so it binds with receptors in the brain, activates them over and over, and creates an excess flood of GABA.
Generally, it’s more difficult than many people would assume to identify the signs of Mysoline addiction. When people think of prescription medication abuse, they usually think of painkillers such as Vicodin or OxyContin, benzodiazepines such as Xanax, or stimulants such as Adderall. Therefore, Mysoline misuse and abuse may fly under the radar until it’s escalated to full-blown addiction.
Here are some of the physical and mental side effects of Mysoline abuse:
Abuse evolves into addiction when someone loses the ability to control their drug use and slips into compulsive use, even if it starts negatively impacting their relationships, finances, and health.
After using Mysoline becomes the focus of someone’s life, the behaviors corresponding with substance use disorders will become more and more apparent. At this point, they will include:
Generally, medical detoxification is the first step in the treatment of any addictive substance. It involves flushing out any trace of drugs or alcohol from the body, in order to stabilize the user and treat any damage these substances are causing.
In particular, Mysoline detox should never be attempted without experienced medical supervision. As a barbiturate, this drug has withdrawal symptoms that are extremely similar to those of benzodiazepines, including delirium, hallucinations, seizures, memory loss, and suicidal behavior.
Without proper medical supervision, Mysoline detox can be unpredictable and even fatal. At a professional detox, a user can be assured of their safety, and they can be provided with detox medications that will help manage the worst of their withdrawal symptoms.
After someone has completed detox, it is strongly recommended that they continue in an inpatient or outpatient recovery program. Detox will get some users sober, but in order to prevent relapse, they need to properly address all aspects of their Mysoline addiction through ongoing care.
If a user has a severe addiction or a history of relapse, living onsite may be the best option. However, if someone is in the early stages of addiction and has a strong support network, then commuting to the center for regular therapeutic sessions might be more beneficial.
Both options involve the client working to better understand their addiction and learning how to it manage it in an efficient, positive manner that is conducive to maintaining long-term sobriety. Here are some of the therapies and treatment modalities commonly utilized during this process:
Mysoline and other barbiturates are rarely used today, which should be a strong indicator of their potential danger. Even using Mysoline as prescribed can have serious side-effects. When abused, Mysoline can cause heart disease, osteoporosis, and permanent memory loss.
Mysoline has an extremely high risk of overdose, which only becomes more likely when someone uses it combination with other depressants, such as opioids or alcohol. Common signs of a Mysoline overdose include:
A Mysoline overdose can be more than enough to kill someone, but the complications caused by it can also prove fatal. They include the buildup of an excess lung fluid known as pulmonary edema and the failure of the heart, kidney, or liver.
Is your loved one struggling with Mysoline abuse or addiction? Are you? If so, it’s important for you to treat it with the seriousness it requires and get help before it’s too late.
Allan, A. M., Zhang, X., & Baier, L. D. (2003, March). Barbiturate Tolerance: Effects on GABA-Operated Chloride Channel Function. Retrieved from https://www.sciencedirect.com/science/article/pii/000689939291583Z?via=ihub
U.S. Drug Enforcement Administration. (2017, June). Drugs of Abuse: A DEA Resource Guide. Retrieved from https://www.dea.gov/sites/default/files/2018-06/drug_of_abuse.pdf
U.S. National Library of Medicine. (2017, September). Barbiturate Intoxication and Overdose. Retrieved from https://medlineplus.gov/ency/article/000951.htm