Mirtazapine and Zopiclone: Which is Stronger?

Medically Reviewed

Going through brief periods of sadness in life is something to be expected. Maybe your pet recently passed away, or perhaps a company declined you from your dream job after a solid interview. In a healthy brain, we will process these emotions and get over them in time. For those struggling with depression, moving on from this immense sadness becomes routine. A person with depression will feel sorrow for no given reason. Unfortunately, it may cause them to need medication to balance their brain chemistry.

The Mayo Clinic defines major depressive disorders, or clinical depression, as a mood disorder that causes persistent feelings of sadness that lead to a loss of interest in life. As the condition deteriorates, it will start affecting how you behave, think, and feel. It will eventually lead to emotional and physical issues, and you will notice problems in how you conduct your day-to-day activities. In severe cases, individuals may feel they aren’t worthy of being alive.

For decades, individuals believed depression could be controlled. This is where the stigma comes from surrounding mental illness. Unfortunately, it’s a chemical imbalance in the brain that requires medication. One of the drugs used to treat depression is known as mirtazapine. It belongs to a class of medicines known as tetracyclic antidepressants.

Despite the extensive research put into mirtazapine, researchers are still unsure how it works in the brain. What they do know, however, is that it affects communications between the nerve cells that restore chemical balance in our brain. In some cases, depression causes insomnia, which requires other medications like zopiclone to be used in conjunction with antidepressants.

Nearly 15 percent of adults with depression can’t sleep well, and insomnia typically accompanies a person struggling with depression. An estimated 80 percent will have trouble falling asleep, and those with insomnia are three times more likely to develop depression.

The relationship between these disorders is unique, but insomnia is seen as a symptom of depression. Doctors feel that treating the underlying depression will help sleep problems vanish, but that’s not always the case.

Is Mirtazapine Or Zopiclone Stronger?

If you were prescribed mirtazapine and struggled with insomnia, your doctor may have included zopiclone into your nightly routine. If you are struggling and your doctor has considered prescribing you this medication in conjunction with your antidepressant, you may be wondering if one drug is stronger than the other.

The National Institutes of Health released a study on this topic and described how mirtazapine could be an effective treatment of insomnia. Many of those struggling with insomnia may be at risk of suicidal ideation, and the therapeutic benefit of targeting insomnia is vital.

It’s not an easy discussion when it comes to which drug is more potent because the two medications fall under different classes. Zopiclone treats insomnia, while mirtazapine is shown to treat both disorders. Based on this factor alone, you might feel comfortable giving mirtazapine the edge on which medication is stronger since it addresses both disorders.

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